Beilstein J. Org. Chem.2013,9, 2129–2136, doi:10.3762/bjoc.9.250
purity was observed.
Keywords: N-(2,3-dihydroxypropyl)arylamide; nitrogen heterocyclic carbenes (NHC); oxidativeesterificationofaromaticaldehyde; Introduction
Chiral structures with three carbons are an integral part of many biologically active compounds including alkaloids, pharmaceuticals and
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Graphical Abstract
Scheme 1:
Retro synthetic approach for the construction of N-(2,3-dihydroxypropyl)arylamides.